Friday, May 31, 2013

Small dams on Chinese river harm environment more than expected, study finds

May 30, 2013 ? A fresh look at the environmental impacts of dams on an ecologically diverse and partially protected river in China found that small dams can pose a greater threat to ecosystems and natural landscapes than large dams. Although large dams are generally considered more harmful than their smaller counterparts, the research team's surveys of habitat loss and damage at several dam sites on the Nu River and its tributaries in Yunnan Province revealed that, watt-for-watt, the environmental harm from small dams was often greater -- sometimes by several orders of magnitude -- than from large dams.

Because of undesirable social, environmental, and political implications, the construction of large dams often stirs controversy. Current policies in China and many other nations encourage the growth of the small hydropower sector. But, "small dams have hidden detrimental effects, particularly when effects accumulate" through multiple dam sites, said Kelly Kibler, a water resources engineer who led this study as part of her PhD research while at Oregon State University in Corvallis. "That is one of the main outcomes of this paper, to demonstrate that the perceived absence of negative effects from small hydropower is not always correct."

She and Desiree D. Tullos, also a water resources engineer at Oregon State and Kibler's PhD advisor, report their findings in a paper accepted for publication in Water Resources Research, a journal of the American Geophysical Union. Kibler now works as a researcher at the International Centre for Water Hazard & Risk Management in Tsukuba, Japan, and as an Associate Professor at Japan's National Graduate Institute for Policy Studies in Tokyo.

To compare the impacts of small and large dams, Kibler investigated 31 small dams built on tributaries of China's Nu River and four large dams proposed for the main stem of the Nu River. She assessed the environmental effects of these dams in 14 categories, including the area and quality of habitat lost, the length of river channel affected, the amount of conservation land impacted, and the landslide risk. Because information regarding large dams is restricted under the Chinese State Secrets Act, Kibler modeled the potential effects of the four large dams using publically-available information from hydropower companies, development agencies, and academic literature.

After evaluating data from the field, hydrological models, and Environmental Impact Assessment reports about the small dams, Kibler and Tullos concluded that impacts of the small dams exceeded those of large dams on nine of the 14 characteristics they studied.

One particularly detrimental impact of the small dams observed in this study is that they often divert the flow of the river to hydropower stations, leaving several kilometers of river bed dewatered, Kibler explained.

From its headwaters in the Tibetan Plateau, the Nu River flows through China, Myanmar (Burma) and Thailand. "While the number of small hydropower dams in operation or planned for tributaries to the Nu River is unreported," the authors note in this study, "our field surveys indicate that nearly one hundred small dams currently exist within Nujiang Prefecture alone."

Thirteen large hydropower dams are proposed for the main stream of the Nu River in Tibet and Yunnan Province in China. "No large dams have been built, but there have been reports that site preparations have begun at some proposed dam sites," Kibler said.

Environmental, social, and economic factors make the Nu River basin extremely sensitive to hydropower installations. In addition to supporting several protected species, the region is home to a large proportion of ethnic minorities and valuable natural resources, the authors report in the study. Parts of the Nu River are also designated as a World Heritage site and the Nature Conservancy and Conservation International have delineated stretches of this river and its tributaries as biodiversity hotspots. But proposed hydropower projects are threatening these statuses, according to Kibler.

While large hydropower projects are managed by the central government, and both large and small hydropower projects undergo environmental impact assessments, decisions about small hydropower projects are made at a provincial or other regional level and receive far less oversight, Kibler and Tullos state in their paper.

Small dams in China "often lack sufficient enforcement of environmental regulations" because they are "left to the jurisdiction of the province," said Guy Ziv, lead scientist for the Natural Capital Project, an organization which develops tools to assess and quantify natural resources, and a researcher for the Woods Institute for the Environment at Stanford University. This study, he added, is "an important contribution to the field of natural resource management."

The lack of regulation paired with a dearth of communication between small dam projects in China allows for the impacts to multiply and accumulate through several dam sites, the study authors write.

In order to mitigate the detrimental effects of small dams, there is a "need for comprehensive planning of low-impact energy development." Kibler and Tullos note.

Policies supporting growth in the small hydropower sector are often crafted at the national or international level, Kibler noted. For example, many of the small dams investigated in the new study were supported by the Kyoto Protocol, a 1997 agreement to reduce greenhouse gas emissions.

"The lack of comprehensive analysis regarding cumulative impact of small hydropower," Kibler said, "is a significant research gap with important policy implications."

The National Science Foundation funded this work.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/dnqobyOpz8M/130530095018.htm

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Samsung Galaxy S 4 Active gets approved by FCC with AT&T LTE

Samsung Galaxy S 4 Active gets approved by FCC with AT&T bands

We've already seen pictures (and video) of the water-defiant Samsung Galaxy S 4 Active, so despite its unannounced status, it's difficult to refute its existence. Fortunately, we're starting to get even more evidence that its launch is rapidly approaching, as an AT&T-compliant version of the rugged device -- the SGH-I537 to be exact -- has made its way through the federal approval process. As you may already know, this is by no means any guarantee that it will be picked up by the mammoth GSM operator, but its inclusion of the same four LTE bands found in most current AT&T smartphones (2, 4, 5 and 17, if you're curious) is a pretty positive indicator. We're still in the woods as to the exact specs, but we're bracing ourselves for a midrange handset that doesn't sport quite the same oomph as its original namesake; that said, it appears to at least be a slick-looking rugged device, which is a rarity these days. It wouldn't surprise us to see this beaut in its full sporty glory June 20th in London, but we'll have to wait it out a few weeks to know if our hunch was right.

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Source: http://www.engadget.com/2013/05/29/samsung-galaxy-s-4-active-fcc/?utm_medium=feed&utm_source=Feed_Classic&utm_campaign=Engadget

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Why animals compare the present with the past

May 30, 2013 ? Humans, like other animals, compare things. We care not only how well off we are, but whether we are better or worse off than others around us, or than we were last year. New research by scientists at the University of Bristol shows that such comparisons can give individuals an evolutionary advantage.

According to standard theory, the best response to current circumstances should be unaffected by what has happened in the past. But the Bristol study, published in the journal Science, shows that in a changing, unpredictable world it is important to be sensitive to past conditions.

The research team, led by Professor John McNamara in Bristol's School of Mathematics, built a mathematical model to understand how animals should behave when they are uncertain about the pattern of environmental change. They found that when animals are used to rich conditions but then conditions suddenly worsen, they should work less hard than animals exposed to poor conditions all along.

The predictions from the model closely match findings from classic laboratory experiments in the 1940s, in which rats were trained to run along a passage to gain food rewards. The rats ran more slowly for small amounts of food if they were used to getting large amounts of food, compared to control rats that were always rewarded with the smaller amount.

This so-called 'contrast effect' has also been reported in bees, starlings and a variety of mammals including newborn children, but until now it lacked a convincing explanation.

Dr Tim Fawcett, a research fellow in Bristol's School of Biological Sciences and a co-author on the study, said: "The effects in our model are driven by uncertainty. In changing environments, conditions experienced in the past can be a valuable indicator of how things will be in the future."

This, in turn, affects how animals should respond to their current situation. "An animal that is used to rich conditions thinks that the world is generally a good place," Dr Fawcett explained. "So when conditions suddenly turn bad, it interprets this as a temporary 'blip' and hunkers down, expecting that rich conditions will return soon. In contrast, an animal used to poor conditions expects those conditions to persist, and so cannot afford to rest."

The model also predicts the reverse effect, in which animals work harder for food when conditions suddenly improve, compared to animals experiencing rich conditions all along. This too has been found in laboratory experiments on a range of animals.

The Bristol study highlights unpredictable environmental fluctuations as an important evolutionary force. "Rapid changes favour individuals that are responsive and able to adjust their behaviour in the light of past experience," said Dr Fawcett. "The natural world is a dynamic and unpredictable place, but evolutionary models often neglect this. Our work suggests that models of more complex environments are important for understanding behaviour."

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_environment/~3/aIWs62NcHWE/130530142003.htm

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Enhance the Speed of Children's Speech with Speech Therapy for ...

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Wellington, Florida ? Children of all ages can perfect their articulation and get a head start in speaking with Speech Therapy for Apraxia 1.2 for iOS and Android. Developed by Blue Whale Apps and a certified Speech-Language Pathologist (SLP) from the National Association for Child Development (NACD), Speech Therapy for Apraxia helps individuals practice speaking by presenting a variety of phonemes and moving through a gentle progression of levels that challenge motor planning for speech. Adults with apraxia/dyspraxia, parents and therapists working with children with apraxia, those learning English as a second language and even children just learning to talk can all boost their speaking proficiency by conveniently practicing with the Speech Therapy for Apraxia suite of tablet apps for iPad, Kindle, Nook and Android tablets.

Perennially in the Top 25 Medical category for paid iPad apps, Speech Therapy for Apraxia is the # 1 speech therapy app available on the market. The app organizes groups of consonants in eight levels roughly by developmental difficulty and place of articulation (bilabial vs. labial). Beginning with a consonant group of their choice, users learn the production of syllables by completing repetitive activities in which they produce different sounds. The lessons progress through increasingly difficult production sequences all the way to the production of sequences of random syllables. The app also includes artfully drawn illustrations, audio and repeat features to support users as they practice each sequence.

?Activities that are commonly used to remediate problems or delays in developing speech can also be used with typically-developing children to help facilitate their development,? said NACD Speech-Language Pathologist Lori Riggs. ?Motor planning for speech (affected in individuals with apraxia) is a skill that toddlers develop as they start to vocalize. Speech Therapy for Apraxia is a fun app that parents can use with both their young, developing children and children with apraxia to help develop their speaking skills.?

?Speech Therapy for Apraxia is an essential tool for anyone who wants to better their speech,? said Gregg Weiss, Founder of Blue Whale Apps.?Personally, I can attest to the app?s effectiveness in treating my daughter?s apraxia as well as its role in assisting my 19 month old son to speak. I?d recommend this app for anyone with an infant or toddler.?

Speech Therapy for Apraxia is the first of the NACD?s line of apps. Speech Therapy for Apraxia ? Words, the organization?s second release, builds on the lessons taught in the original app by focusing on the production of words.

Speech Therapy for Apraxia Features
* Choose from 8 different consonant groups (for a total of 19 consonant sounds) to target
* For each group, choose from 8 levels to practice
* Detailed instructions explain how to choose an appropriate consonant group and practice level
* Move through a logical progression of 8 different levels for motor planning for speech
* Illustrations and audio provided for each syllable
* Option to repeat levels, reset, or move to next level
* Can also be used for straight articulation drill for particular phonemes

About NACD:
The National Association for Child Development is a unique organization with a unique approach to brain growth and development. Founded in 1979 by Bob Doman, NACD has helped parents enhance the development and function of their children for over 30 years. In its work with tens of thousands of clients, NACD has developed an approach to human development, the achievement of human potential, and the remediation of developmental, educational, and neurological problems that is based upon the gestalt of the individual. The efficacy of NACD?s Targeted Developmental Intervention has been demonstrated with individuals from infant to geriatric, whose function has ranged from comatose to gifted. It is from this background and experience that the NACD team of neurodevelopmentalists and therapists, including speech/language pathologists, has created the NACD Home Speech Therapist line of speech apps.

Device Requirements:
* Requires iPad with iOS 4.3 or later
* 10.3 MB

Pricing and Availability:
Speech Therapy for Apraxia 1.2 is $4.99 USD (or equivalent amount in other currencies) and available worldwide through the App Store in the Medical category. It is also available on Google Play, Amazon App Store and Nook Store. For more information on Speech Therapy for Apraxia and Speech Therapy for Apraxia ? Words please visit the app website.

Speech Therapy for Apraxia 1.2
Purchase and Download
YouTube Video
Screenshot 1
Screenshot 2
Screenshot 3

Blue Whale Apps is a mobile app development company specializing in high quality and engaging iPhone/iPad apps for medical professionals and the healthcare industry. Blue Whale brings you a team of highly experienced professionals who?ve worked with the world?s leading technology, advertising and design companies. Copyright (C) 2013 Blue Whale Apps. All Rights Reserved. Apple, the Apple logo, iPhone, iPod and iPad are registered trademarks of Apple Inc. in the U.S. and/or other countries. All other trademarks and trade names are the property of their respective owners.

Related Posts B

  1. Blue Whale Apps and NACD Release Second Speech Therapy Apps
  2. The iMums Feature Speech Therapy Apps for Better Hearing and Speech
  3. Speech and Language Therapy Apps Showcased During The iMums Event Week
  4. Speech Remedy Launches Speech Therapy App to Rebuild Language Skills
  5. A Speech Therapy App For Learning How To Express Colors

Source: http://www.slapapp.com/enhance-the-speed-of-childrens-speech-with-speech-therapy-for-apraxia/

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Syrian Civil War Forces Sunni And Shiite Muslims To Pick Sides

By Oren Dorrell and Ahmed Kwider
USA Today

AMMAN, Jordan (RNS) The Syrian civil war is increasingly drawing in nations across the Middle East, a regionwide conflict that threatens to pit world powers against each other and Muslim against Muslim.

On Wednesday (May 29), the United Nations Human Rights Council pushed through a resolution to investigate the abuses of the Syrian regime, over the objections of the regime?s ally Russia, who insisted the West was making matters worse.

U.S. Secretary of State John Kerry continued his travels in the region, trying to get all parties to agree to a peace conference in Geneva in the next few weeks. But councils representing the Syrian rebels again refused to join, demanding that representatives of Bashar Assad?s regime be banned.

In a war that is now clearly pitting the two main branches of the Islam ? Sunni and Shiite Muslims ? against one another, the dithering and differences between world powers is bringing about a desperate situation, according to experts.

?The longer this conflict goes on the more chances it has of spilling over,? said Vali Nasr, dean of John Hopkins University?s Paul H. Nitze School of Advanced International Studies in Washington.

Whether the battle will be contained to Syria is in doubt now that Islam?s two major strands have taken sides against one another, threatening to spark a wider war that is centuries in the making between Sunni and Shiite Muslims.

?There is great fear over a massive sectarian war starting. If it does, the entire region will turn into a genocidal war, engulfing everyone,? says Samir al-Ibrahim, 55, secretary-general of the Syrian Free Religious Scholars Association and a Sunni Muslim in Idlib, Syria.

Sunni Muslims, who include the royal families of the Persian Gulf oil sheikdoms, have banded behind the rebels (Sunnis are the majority in Syria). The royal family of Saudi Arabia and Qatar have been funneling arms and cash to rebels, and Sunni Muslims who dominate al-Qaida have dispatched fighters to the front.

Assad has appealed to the Shiites, who are helping him hang on to his regime. The Shiite theocracy of Iran has deployed officers and fighters from its Revolutionary Guards. The U.S.-designated terrorist group Hezbollah, which has fought two wars with Israel from its base in Lebanon, is pouring militants into Assad?s forces.

Religious leaders from both Islamic branches in Sunni-dominated Egypt and Shiite-heavy Iraq have denounced each other for killing Muslims. Arab capitals have expressed fears that restive members of one sect or the other will erupt in the streets as they did in Bahrain during the Arab Spring of 2011.

Already, the fighting has bled across Syria?s border with Lebanon, where Lebanese Alawites are fending off attacks from Sunni citizens of the same nation, leaving several people dead. Rockets have been fired back and forth between Turkey and Syria and Iraq.

The schism that gave birth to the Sunni and Shiite divide occurred in the seventh century soon after the death of Islam?s Prophet Muhammad.

Some Islamic leaders took the position that it was legitimate for Muhammad?s successor to be chosen through consultation, and they selected the father of Muhammad?s wife to be caliph, or leader of the Muslim world. They became the Sunnis.

Others believed Muhammad intended his cousin and son-in-law Ali, a blood relative, to be his rightful heir. They became the Shiites.

The disagreement led to war. Ali was killed as were his two sons. The two branches flourished as the Shiites, translated roughly as ?the followers of Ali,? and the Sunnis, ?the people of the tradition of Muhammad and the consensus of the Ummah,? or the Islamic world.

Over the centuries, there were many conflicts. The Sunnis achieved dominance in numbers, wealth and power. The Sunnis of the Ottoman Empire based in modern-day Turkey swept through the Arab world in the Middle East and controlled the caliphate for centuries until World War I.

The victorious allied powers divided up the empire into nations, turning power over to their favored tribes and leaders in newly created countries such as Syria, Iraq and Saudi Arabia ? but they also threw together Sunnis and Shiite communities and largely left Sunnis in positions of power.

Today, Sunnis are the majority in most Muslim countries, except in Iraq, Lebanon, Bahrain and Iran. Assad?s Alawite sect is an offshoot of Shiite Islam.

One reason given by the Obama administration for refusing to arm rebels to topple a man it wants gone is concern over who will replace him. Sunni foreigners allied with al-Qaida have been streaming into the fight and winning some battles.

Abu Said, 35, a Sunni member of the Revolution Council in Outer Damascus, a rebel group, says foreign fighters fill a void for anti-government fighters who are outgunned and out-funded by Assad?s forces.

?As for al-Qaida, it?s not only our problem, but yours too,? Said added referring to the West. ?You?ve allowed our country to become a feasible environment for everyone to operate, whether al-Qaida, Hezbollah, or Iran?s and Iraq?s volunteers.?

Adnan Oumama, a hard-line Lebanese Sunni sheikh, sees the strife already bleeding into his country.

?There is no doubt that the war in Syria has turned into a sectarian conflict pitting Shiites and Alawites against Sunnis,? Oumama said. ?We are against a religious war with the Shiites, but if someone starts killing us based on our religion, we will defend ourselves.?

Shiite cleric Sheik Mohamad Ali Hajj el Ameli also sees the Syrian sectarian war spreading to Lebanon.

?The Muslim street, whether Sunni or Shiite has radicalized,? Ameli said, ?Although politicians do not seem to want a war in Lebanon, it is doubtful they can maintain control of their followers, given the involvement of both communities in Syria. A religious war is thus a growing possibility, all the signs are pointing to one.?

(A longer version of this story originally appeared in USA Today, reported by Oren Dorell and Ahmed Kwider with contributions from Mona Alami.)

Also on HuffPost:

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Source: http://www.huffingtonpost.com/2013/05/30/syrian-civil-war-forces-sunni-and-shiite-muslims-to-pick-sides_n_3362357.html

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Autopsy: UK soldier died from cuts, stab wounds

LONDON (AP) ? An autopsy shows that a British soldier killed in a suspected Islamic extremist attack in London last week died from multiple cuts and stab wounds after he was hit by a car, police said Wednesday.

Lee Rigby, 25, was first struck by a blue car and then stabbed by two men near his barracks in southeast London's Woolwich district, police said.

Images that emerged in the attack's aftermath showed two men wielding bloody knives and meat cleavers. Police said the autopsy showed Rigby died from "multiple incised wounds."

Both prime suspects were shot and wounded by police at the scene. Suspect Michael Adebolajo, 28, remains hospitalized in stable condition while Michael Adebowale, 22, was discharged from a hospital Tuesday and is in police custody.

A total of 10 people have been arrested in the case, including the two main suspects. Two people were released and several others have been set free on bail pending further inquiries. No charges have been filed yet.

With the cause of death established, police said an inquest on Rigby's death will open Friday at Southwark Coroner's Court. In Britain, inquests are conducted to establish the circumstances surrounding unexpected or violent deaths.

London counterterrorism police officers handed out leaflets Wednesday seeking information from pedestrians and bus passengers in a quest for new information on the slaying that shocked Britain.

One of the men arrested for questioning in the case released a statement through his lawyer Wednesday proclaiming his innocence. Hayden Allen, 21, said in the statement that he wanted to send his condolences to Rigby's family.

"My family are wholly uninvolved," said Allen, who has not been charged and is free on bail. "I ask that the police continue to investigate and that my family be allowed without harassment to continue their lives."

The killing of an off-duty soldier by suspected Islamic militants has raised racial enmities in many parts of England, with far-right groups mobilizing to protest.

British prison officers have been warned to be on the lookout after a hostage drama blamed on extremist Muslim inmates, British newspapers reported Wednesday.

An email to high-security prisons and young offenders' institutes warned that Sunday's incident at Full Sutton detention facility in the northern England region of Yorkshire was linked to religious extremism and warned of an increased risk of attacks at other institutions, according to several British papers, including The Yorkshire Post and The Times.

"Three Muslim prisoners took an officer hostage in an office. Their demands indicated they supported radical Islamist extremism," the letter was quoted as saying. "All staff are reminded to remain vigilant to the increased risk of potential attacks on prison officers inspired by these and last Wednesday's events."

The hostage-takers demands have not been disclosed. Britain's Ministry of Justice declined to comment on the email.

The English Defense League, a right-wing group with strong anti-Islam leanings, has held a series of protests in the wake of the killing, while Muslim community organizations have reported a surge in attacks and harassment.

One mosque in the northern England town of Grimsby was firebombed, and the word "ISLAM" was daubed in big red letters across the Royal Air Force Bomber Command memorial in London's Green Park, near Buckingham Palace.

Two people have been charged in the arson attack. It's unclear who was responsible for the graffiti.

Hackers have also posted a purported list of English Defense League leaders and supporters to the Internet. The list was at least partially genuine, according to English Defense League supporter Glen Warren, 32, whose name and phone number were among those made available online.

___

Cassandra Vinograd contributed to this report.

Source: http://news.yahoo.com/autopsy-uk-soldier-died-cuts-stab-wounds-142248784.html

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Thursday, May 30, 2013

Wit, grit and a supercomputer yield chemical structure of HIV capsid

May 29, 2013 ? A team led by researchers at the University of Pittsburgh School of Medicine has described for the first time the 4-million-atom structure of the HIV's capsid, or protein shell. The findings, highlighted on the cover of the May 30 issue of Nature, could lead to new ways of fending off an often-changing virus that has been very hard to conquer.

Scientists have long struggled to decipher how the HIV capsid shell is chemically put together, said senior author Peijun Zhang, Ph.D., associate professor, Department of Structural Biology, University of Pittsburgh School of Medicine.

"The capsid is critically important for HIV replication, so knowing its structure in detail could lead us to new drugs that can treat or prevent the infection," she said. "This approach has the potential to be a powerful alternative to our current HIV therapies, which work by targeting certain enzymes, but drug resistance is an enormous challenge due to the virus' high mutation rate."

Previous research has shown that the cone-shaped shell is composed of identical capsid proteins linked together in a complex lattice of about 200 hexamers and 12 pentamers, Dr. Zhang said. But the shell is non-uniform and asymmetrical; uncertainty remained about the exact number of proteins involved and how the hexagons of six protein subunits and pentagons of five subunits are joined. Standard structural biology methods to decipher the molecular architecture were insufficient because they rely on averaged data, collected on samples of pieces of the highly variable capsid to identify how these pieces tend to go together.

Instead, the team used a hybrid approach, taking data from cryo-electron microscopy at an 8-angstrom resolution (a hydrogen atom measures 0.25 angstrom) to uncover how the hexamers are connected, and cryo-electron tomography of native HIV-1 cores, isolated from virions, to join the pieces of the puzzle. Collaborators at the University of Illinois then used their new Blue Waters supercomputer to run simulations at the petascale, involving 1 quadrillion operations per second, that positioned 1,300 proteins into a whole that reflected the capsid's known physical and structural characteristics.

The process revealed a three-helix bundle with critical molecular interactions at the seams of the capsid, areas that are necessary for the shell's assembly and stability, which represent vulnerabilities in the protective coat of the viral genome.

"The capsid is very sensitive to mutation, so if we can disrupt those interfaces, we could interfere with capsid function," Dr. Zhang said. "The capsid has to remain intact to protect the HIV genome and get it into the human cell, but once inside it has to come apart to release its content so that the virus can replicate. Developing drugs that cause capsid dysfunction by preventing its assembly or disassembly might stop the virus from reproducing."

The project was funded by National Institutes of Health grants GM082251, GM085043 and GM104601 and the National Science Foundation.

"By using a combination of experimental and computational approaches, this team of investigators has produced a clearer picture of the structure of HIV's protective covering," said the National Institutes of Health's Michael Sakalian, Ph.D., who oversees this and other grants funded through an AIDS-related structural biology program. "The new structural details may reveal vulnerabilities that could be exploited by future therapeutics."

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/tMgcKXARwnE/130529133403.htm

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Business groups call on White House, Congress to boost quality preschool (Washington Bureau)

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Interleukin-22 protects against post-influenza bacterial superinfection

Interleukin-22 protects against post-influenza bacterial superinfection [ Back to EurekAlert! ] Public release date: 30-May-2013
[ | E-mail | Share Share ]

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology

Researchers from the Pasteur Institute, Lille, France have shown in a mouse model that interleukin-22 protects against bacterial superinfections that can arise following influenza. Their research is published in the June 2013 issue of the Journal of Virology.

Influenza A viral infection can lead to primary pneumonia and, later on, to serious complications including secondary bacterial pneumonia and sepsis. Post-influenza bacterial superinfections that occur during seasonal epidemics and pandemics are of great concern to human health and impose a considerable socio-economic burden.

"It is therefore critical that we reach a better understanding of the causes of and potential treatments for post-influenza bacterial superinfection," says corresponding author Franois Trottein.

"Mouse studies have revealed that impairment of the host innate immune defense, as well as lung damage caused by the virus are cardinal features of bacterial superinfection," says Trottein. The authors tested the hypothesis that interleukin-22, an important cytokine implicated in mucosal immunity, inflammation and tissue repair, might play an important role during influenza.

The authors show that several cell types belonging to the innate immune system produce interleukin-22 soon after infection. They also demonstrate that the lack of interleukin-22 aggravates the pathogenesis that develops in the lungs and in particular exacerbates epithelial damage caused by the virus. Furthermore, endogenous interleukin-22 displays a protective role during secondary bacterial (pneumococcus) infection in the mouse system.

Although the mechanisms sustaining the protective effect of interleukin-22 are not yet fully elucidated, the authors speculate that its beneficial effect is due to its role in the maintenance of epithelial integrity.

"If it works as well in humans, the production of interleukin-22 could confer a substantial benefit on patients having flu," says Trottein.

###

A copy of the article can be found online at http://bit.ly/asmtip0513b.

(S. Ivanov, J. Renneson, F. Trottein, et al. Interleukin-22 reduces lung inflammation during influenza A virus infection and protects against secondary bacterial infection. J. Virol. June 2013; 87:12 6911-6924. Published ahead of print17 April 2013. doi:10.1128/JVI.02943-12)

The Journal of Virology is a publication of the American Society for Microbiology (ASM). The ASM is the largest single life science society, composed of over 39,000 scientists and health professionals. Its mission is to advance the microbiological sciences as a vehicle for understanding life processes and to apply and communicate this knowledge for the improvement of health and environmental and economic well-being worldwide.


[ Back to EurekAlert! ] [ | E-mail | Share Share ]

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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Interleukin-22 protects against post-influenza bacterial superinfection [ Back to EurekAlert! ] Public release date: 30-May-2013
[ | E-mail | Share Share ]

Contact: Jim Sliwa
jsliwa@asmusa.org
202-942-9297
American Society for Microbiology

Researchers from the Pasteur Institute, Lille, France have shown in a mouse model that interleukin-22 protects against bacterial superinfections that can arise following influenza. Their research is published in the June 2013 issue of the Journal of Virology.

Influenza A viral infection can lead to primary pneumonia and, later on, to serious complications including secondary bacterial pneumonia and sepsis. Post-influenza bacterial superinfections that occur during seasonal epidemics and pandemics are of great concern to human health and impose a considerable socio-economic burden.

"It is therefore critical that we reach a better understanding of the causes of and potential treatments for post-influenza bacterial superinfection," says corresponding author Franois Trottein.

"Mouse studies have revealed that impairment of the host innate immune defense, as well as lung damage caused by the virus are cardinal features of bacterial superinfection," says Trottein. The authors tested the hypothesis that interleukin-22, an important cytokine implicated in mucosal immunity, inflammation and tissue repair, might play an important role during influenza.

The authors show that several cell types belonging to the innate immune system produce interleukin-22 soon after infection. They also demonstrate that the lack of interleukin-22 aggravates the pathogenesis that develops in the lungs and in particular exacerbates epithelial damage caused by the virus. Furthermore, endogenous interleukin-22 displays a protective role during secondary bacterial (pneumococcus) infection in the mouse system.

Although the mechanisms sustaining the protective effect of interleukin-22 are not yet fully elucidated, the authors speculate that its beneficial effect is due to its role in the maintenance of epithelial integrity.

"If it works as well in humans, the production of interleukin-22 could confer a substantial benefit on patients having flu," says Trottein.

###

A copy of the article can be found online at http://bit.ly/asmtip0513b.

(S. Ivanov, J. Renneson, F. Trottein, et al. Interleukin-22 reduces lung inflammation during influenza A virus infection and protects against secondary bacterial infection. J. Virol. June 2013; 87:12 6911-6924. Published ahead of print17 April 2013. doi:10.1128/JVI.02943-12)

The Journal of Virology is a publication of the American Society for Microbiology (ASM). The ASM is the largest single life science society, composed of over 39,000 scientists and health professionals. Its mission is to advance the microbiological sciences as a vehicle for understanding life processes and to apply and communicate this knowledge for the improvement of health and environmental and economic well-being worldwide.


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AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.


Source: http://www.eurekalert.org/pub_releases/2013-05/asfm-ipa053013.php

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Is Venezuela's opposition TV channel bowing to government pressure?

A spate of journalist firings and resignations at the traditionally opposition station Globovisi?n has some worried that the opposition has lost its voice in the media landscape.

By Hugo P?rez Hern?iz,?WOLA, David Smilde,?WOLA / May 30, 2013

Screens are seen at the master room of Venezuela's opposition TV station Glob?vision in Caracas, Tuesday.

Jorge Silva/Reuters

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??David Smilde is the moderator of WOLA's blog:?Venezuelan Politics and Human Rights.?The views expressed are the author's own.

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What originally appeared as a visible but subtle change of direction at Venezuelan television station Glovovisi?n has in the last two weeks become a raucous turning point with multiple journalists being fired or resigning. The turmoil leaves Globovisi?n?s role as an opposition outlet in doubt and appears to represent a new extension of the Venezuelan government?s control over broadcast media.

Following Guillermo Zuloaga?s announcement in March that he had agreed in principle to the sale of Globovisi?n it was finally acquired at the beginning of May by a business group rumored to have ties with the Government.

The announcement of the hiring of journalists Vladimir Villegas and Leopoldo Castillo as station directors generated considerable optimism about the new Globovisi?n and its independence. However on May 13, after a meeting with the new owners, Mr. Villegas surprisingly announced on Twitter that he would not be accepting the position after all. He commented that ?we didn?t reach agreement on programming nor on what my competencies would be.??

One of the new owners, Juan Domingo Cordero, declared on May 16 that there had been disagreements in the meeting with Villegas over the general direction the business should follow, but he assured that there would be no changes in the channel and that all the journalists would keep their jobs: ?All the news anchors are staying, there won't be any changes here.?

However events have unfolded quite differently.

On May 22, President Nicol?s Maduro met with two of the new owners of the Channel, Ra?l Corr?n and Gustavo Perdomo, in Miraflores. The meeting was qualified by the business men as ?cordial? and they declared that they had told President Maduro that Globovisi?n would contribute to ?the decrease in the levels of violence in the country.? Information Minister Jorge Arreaza, also present in the meeting, revealed that Maduro had insisted on the need for ?generating television content with transcendent values for the future of the children and the need to struggle against fascism, which is a threat to society in any part of the world.?

Only two days after that meeting with the government, Globovisi?n confirmed rumors that Ismael Garc?a (opposition National Assembly representative and responsible for making public the Mario Silva audio) would leave his morning opinion program ?Al? Venezuela.? The program will still be aired with co-host Delvalle Canel?n but without Mr. Garc?a. The statement explained that the policy of the channel was not to air programs hosted by candidates for political office, and since Garc?a would be a candidate for Mayor of Caracas in the upcoming municipal elections, the channel had asked him to leave the program. In Venezuela it is common for elected leaders and candidates for office to simultaneously work as broadcast journalists.

The next day the channel also announced that the popular late night host of the show ?Good Night,? Francisco Bautista ?Kiko,? would leave Globovisi?n. On the same night of the 26th Henrique Capriles tweeted several times about Globovisi?n. He expressed solidarity with the workers of the channel and claimed that the new owners had given express orders not to provide live coverage of his speeches and declarations.

On Monday the 27th, news anchor Pedro Luis Flores, and ?Buenas Noches? cohost Carla Angola announced they had quit Globovisi?n in solidarity with Kiko. The Globovisi?n web page announced the reporters where leaving the channel on ?the best of terms.? That same day Globovisi?n published a statement on its web page reaffirming that the exit of Garc?a had been on friendly terms and that Kiko had made misinformed declarations on the matter. The statement denies the existence of a ?list of professionals? that will be fired, and ends with the assertion that ?media outlets are not political parties.?

That same afternoon, reporter Leopoldo Castillo (popular host of the show ?Al? Ciudadano? and now temporary director of Globovisi?n), in a statement aired by Globovisi?n declared that there had been misunderstandings recently and that he would do everything in his power to keep the channel?s personnel ?united,? but if that was not possible, he would simply leave. He also asked his fellow reporters to ?not respond emotionally? and impulsively. He added that if he discovered recent events in the channel where part of a ?systematic policy, which up to date I have not uncovered, you can be sure that I will speak out.? (The video can be seen here.)

That same night Kiko declared to CNN en Espa?ol that his meeting with the new owners of the channel had been ?very aggressive?, and that they had ?used the same arguments that the oficialismo [government] uses to attack me. They told me that the channel had been used as a political party and was responsible for what had happened in the country. They told me that I used slander and that I made fun of people.? He also denounced that the day Ismael Garc?a had made public the Mario Silva audio, in several occasions they had tried to take it off the air ?and then that night at news hour, when that information was given, the reporter that wrote the note said that it had been edited. They took out the parts where Diosdado Cabello was named.?

In a press conference, Kiko reiterated that the new board of directors is exercising censorship in line with the Government. He also declared that during his last meeting with the new directors, they had offered to buy the name of the show ?Buenas Noches,? which Kiko owns, but that he had refused.

On Tuesday May 28?Maduro declared that the problem with Globovisi?n is not disagreements over a supposed change of editorial line but a fight between different factions of the ?right? for control of the channel: ?They are dealing with a huge problem among themselves?In the end they are the ones that are destroying the TV channel that the fascist right used to poison the country: Globovisi?n.?

The Globovisi?n official twitter account has suffered an ?unfollow? campaign by opposition followers unhappy with what they perceive is a change in the editorial line of the channel. According to Noticias 24, the account had 2,732,394 followers on Sunday 26th. At the time of writing this post the account has 2,349,779 followers.

? ?David Smilde is the moderator of WOLA's blog:?Venezuelan Politics and Human Rights.?

The Christian Science Monitor has assembled a diverse group of Latin America bloggers. Our guest bloggers are not employed or directed by the Monitor and the views expressed are the bloggers' own, as is responsibility for the content of their blogs. To contact us about a blogger, click here.

Source: http://rss.csmonitor.com/~r/feeds/csm/~3/TKDyx1V_Suk/Is-Venezuela-s-opposition-TV-channel-bowing-to-government-pressure

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Telly Releases Android Tablet App As It Approaches 70K Likes Per Week On Google's Mobile OS

popularVideo discovery service Telly is launching its social video app on Android tablets today, a key step for the company as Google's mobile OS becomes more important to its overall strategy and audience. Android engagement is growing quickly, the company has told TechCrunch exclusively, with Likes per week growing at a rapid pace, jumping from below 50,000 the week of May 17, to over 70,000 during the week of May 24. Telly also had 4.8 million views across all mobile platforms last week, which was up from 3 million the week prior.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/4GsLqWx1d1k/

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This Guy Proposed to His Girlfriend with... Vine

This Guy Proposed to His Girlfriend with... Vine

I don't even... This is just... I can't believe... okay. Breathe. Some guy used Vine and Twitter to propose to his girlfriend. As in he recorded a six second Vine video (selfie?) asking her to marry him, with a ring and everything. She didn't say no.

Read more...

    


Source: http://feeds.gawker.com/~r/gizmodo/full/~3/8O1kfC7ejZs/this-guy-proposed-to-his-girlfriend-with-vine-510394297

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Re-commerce Gets A Revamp With Threadflip's New iPhone App Built For An Exploding Mobile Audience

ThreadflipiOS-single-item-pageThreadflip, the online and mobile marketplace that helps users clean out their closets, or buy from those who are doing just that, is today introducing a completely revamped mobile experience for its iOS application following a surge of growth from its mobile user base. It’s a welcome change, and one that should help the company better compete with similar services from Poshmark or thredUP, for example. The update comes at a time when everyone is shifting their shopping behavior to mobile, forcing companies to quickly ramp up their mobile experiences to meet that demand. For example, Fab reported last month that a third of its sales were placed via mobile, ModCloth says a quarter of its traffic came from mobile devices?(even before it had released its iPhone app!), and JackThreads just a couple of weeks ago said that nearly half its orders were coming in through mobile. The numbers Threadflip is seeing fit right in with this trend. “We’re noticing a pretty big paradigm shift towards the mobile companion use cases both on the buyer’s side, as well as the seller’s side,” Threadflip CEO and founder Manik Singh tells us. “Forty percent of our daily uploads (people selling items) are coming from mobile. Twenty percent of our daily transactions are coming from mobile. We’re seeing 70 percent of the emails we send to our consumers – both marketing and transactional – opened on mobile devices,” he says. Threadflip’s iOS application was released around a year ago, but it’s only been over the past three to four months that mobile began to take off in a huge way. Singh attributes this shift both to Threadflip’s growing traction as a brand, as well as the fact that, as its users shift from being buyers to sellers, it’s easier to snap photos of their fashion items using their phone’s camera, which then leads them to download the mobile app. What’s New Because of this growing mobile audience, Threadflip wanted to revamp the app to better serve its users’ needs and address their feedback. Most noticeably, the overall appearance has been redesigned. Now, instead of dropping users directly into the shopping experience, the app starts you off on a new homepage where you can choose a category (e.g. clothing, shoes, accessories, all or “Editor’s Picks” for a best-of-the-best view). There’s also a better filtering menu which lets you find items by size, price, category

Source: http://feedproxy.google.com/~r/Techcrunch/~3/0YqsaHa_C-U/

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Sources claim HTC One Google Edition to land in limited Quantities

Google Edition HTC One
Google Edition devices are starting look like the next trend that manufacturers will be shooting for. We all saw the Google Edition Galaxy S4 at Google I/O. While many weren?t to excited about the $650 price tag that was attached to it, the device does have a place in the world. It offers Android users and lovers another device that stock without the need to root, hack or mod their carrier branded version. It also allows Google to push updates out directly to the devices as well. Cutting out that delay between releases, manufacturer branding and carrier branding injections. ?Rumors started flying around at that time that HTC would be producing a Google Edition HTC One as well. Apparently a well-known source has tipped off Pocket-Lint with some more details.

While the source didn?t offer up any particulars, like a date or price point, they did offer up some info on how many will likely be available. Stating that the current plan is for about 1% Google Edition devices of the total HTC One sales numbers. Talks put the HTC One at selling around 5 million units to date, so doing some math puts that at around 50,000 HTC One Google Edition devices to be produced and sold.

We can think of a handful of people who would love to get their hands on a Google Edition HTC One, but we aren?t sure how well this will all play out. Is it worth the money to get a Google Edition device that isn?t a Nexus? Is this all just live field trial to see if it generates enough interest for Google to and the OEMs to start putting out various stock Android devices for users to choose from? I remember a rumor sometime last year that the Nexus 4 wouldn?t be the only Nexus phone released. Turned out to be the tablet line of course. I would love to see each manufacturer work with Google to bring a stock experience of each of their flagship devices to the Play Store, so long as the pricing came down a bit.

Other talks say we should have an announcement about this phone in just a week or so. Seemingly being confirmed by plenty of notable tech enthusiasts such as Russel Holly,?Paul O?Brien?and?@LlabTooFeR.?Will you be hovering over the Play Store, or where ever it might be sold, hitting F5 to be one of the elite owners?

Via AndroidHeadlines?& AndroidCentral

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About the Author

Stormy Beach

Time for an update. I am the proud father of three, 2, 8, and 11. I finally just moved up from the Samsung Vibrant to the Samsung Galaxy S III...... Let me tell you, it is mind blowing. I love Android, I love tech and I love my family. Not in that order though. I work to hard, play even harder and take care of all that are around me when I can.
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Source: http://feedproxy.google.com/~r/androidspin/feed/~3/PS3XTb1qlqM/

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Ancient Cave Art Unearthed in Northeastern Mexico

In northeastern Mexico, archaeologists found ancient paintings on the walls of caves before Spanish rule. (Photo : Reuters)

In northeastern Mexico, archaeologists found ancient paintings on the walls of caves before Spanish rule. Livescience.com reported that the art shows evidence of native cultures that lived in the area around Sierra de San Carlos which is a mountain range in Tamaulipas.

There wer almost 5,000 paintings found in the region. "Created with red, yellow, black and white pigments, the images show animals from deer to lizards to centipedes, as well as people. Depictions of tents, hunting, fishing and possibly?astronomical charts?also offer a glimpse into the life of this mysterious culture," reported Livescience.com.

Archaologist Gustvao Ramirez from the Mexican National Institute of Anthropology and History said in a press release that the discovery shows the presence of pre-Hispanic groups, "where before it was said that there was nothing, when in fact it was inhabited by?one or more cultures."

The Agence France Presse reported that researchers will try to find out the age of the artwork by using chemical and radiocarbon analyses. The colors they used were made using organic dyes and minerals said the INAH press release.

"We have not found any ancient objects linked to the context, and because the paintings are on ravine walls and in the rainy season the sediments are washed away, all we have is gravel," added Ramirez, reported LiveScience.com.

The History Channel said on its website that there may have been nomadic tribes as far back as 6000 BC in Tamaulipas. Then between 1445 and 1466 Aztec armies conquered a lot of the region.

"These tribes of primitive men, women and children resembled wandering gypsies except for the fact that they remained fixed in a natural niche within the boundaries of which they had freedom of movement. They escaped the greedy and authoritarian clutches of the gold-diggers who had arrived from across?the?Atlantic,
?reported I4UNews.com.

The findings were presented ?recently during the Second Conference of Archaeological History in Mexico City.

Source: http://www.travelerstoday.com/articles/6414/20130528/ancient-cave-art-unearthed-northeastern-mexico.htm

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Wednesday, May 29, 2013

Kansas Politicos Return To GOP Gridlock

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Source: http://www.tonyskansascity.com/2013/05/kansas-politicos-return-to-gop-gridlock.html

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Amanda Bynes Tells Her Version of Arrest Story

You'd think that getting arrested might have been a wake-up call for Amanda Bynes. No such luck.

Source: http://www.ivillage.com/amanda-bynes-tells-her-version-arrest-story-denies-rihanna-tweets/1-a-537435?dst=iv%3AiVillage%3Aamanda-bynes-tells-her-version-arrest-story-denies-rihanna-tweets-537435

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Returning to the L.A. River; and going with the flow

Steve Schleier has kayaked spectacular and scenic rivers from West Virginia to Alaska. So when the Los Angeles lawyer heard that his hometown river was opening to public navigation for the first time in decades, he was all in.

It didn't matter that the open section is a mere 21/2 miles long. It didn't matter that the riverbed is lined with concrete. And it didn't matter that the course features more warehouses than white water.

For Schleier, like many Angelenos, the opening of a modest stretch of the Los Angeles River on Monday was about redemption and possibility.

"Today," he said, preparing to put in at Rattlesnake Park, where Fletcher Drive crosses over the water, "is like getting your toe in the water for the revitalization of the river."

Earlier in the day, local officials and river aficionados gathered to celebrate the opening of the section between Fletcher and Oros Street as a recreation zone for the summer. The designation allows people to boat, kayak, walk or fish from dawn to sundown through Labor Day, Sept. 2. In the past, some of those activities have been allowed only by permit.

By the time the L.A. River runs under the bridge at Fletcher, it has coursed and trickled from its source in the Simi Hills before emptying into the Pacific Ocean in Long Beach.

Most of the river was entombed in concrete in the 1930s, a reaction to a series of catastrophic floods. After that, the river became a symbol of Los Angeles' unchecked sprawl, an occasional backdrop for movie car chases ? and punch lines.

In the 1980s, environmental groups began pushing to remove the concrete and return the river to its natural state. Since then, voters have approved millions of dollars in bond measures for the development of recreational opportunities along its course.

In 2011, a scenic portion in the San Fernando Valley's Sepulveda Basin opened for guided tours. Tickets sold out in minutes.

Today, hiking and bicycle trails and pocket parks dot its course, and it serves as a habitat for more than 200 species of birds. The opening ceremony for the recreation zone was at Marsh Park, situated on a once-blighted patch of land in the neighborhood between Interstate 5 and the river.

Speaking at the ceremony, City Councilman Ed Reyes said the park and the recreation zone should be a model for the broader reclamation of the river. It's something he's yearned for since he was a child. When he was growing up, Reyes recalled, the parks were riddled with gangs. So he and his friends hung out at the river, even though it was technically off-limits.

"We needed a sanctuary, a place to go, and the river gave us that," Reyes said. "We were told you couldn't go in, so ? as 10-year-olds ? we went in anyway."

Among the river's champions are Jeff Tipton and Joel Shapiro, two doctors who in 2008 were part of a rogue flotilla that, without permits, kayaked 51 miles of the river over three days to draw attention to the cause. On Monday, they were among the first to try to ply the waterway ? legally.

"This is a great start," Tipton said. "But people need to continue to challenge their access to the river."

Schleier's maiden voyage lasted two hours and included a dip when his kayak tipped over in a rough patch. His buddies, film editor Mark Goldberg and hairstylist Trey Burnette, helped him out of the drink, and the trio ventured on. They saw egrets and ducks. And they marveled at how little trash they saw.

"It was beautiful," Schleier said. "It was a great trip."

lisa.girion@latimes.com

Source: http://feeds.latimes.com/~r/latimes/news/science/~3/VOuSL-GEktE/la-me-la-river-20130528,0,2781147.story

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Tuesday, May 28, 2013

LG Optimus G Pro Review: The Fastest Big Phone Out There

LG Optimus G Pro Review: The Fastest Big Phone Out There


Fun fact: In a sprint, the hippo is one of the fastest land mammals, despite also being one of the largest. Similarly, the LG Optimus G Pro is unquestionably one humungoid phone, but it runs about as fast as the top speedsters out there. Whether or not you should consider buying it, however, is up to the elasticity of your fingers.

What Is It?

It's a bigass phone made by LG to compete with Samsung's bigass phone, the Galaxy Note II. It has a 5.5-inch 1080p HD screen, it's running Android 4.1 (Jelly Bean), and it has Qualcomm's screaming fast quad-core Snapdragon 600 processor clocked at 1.7GHz.

Who's It For?

People who want a lot of screen real-estate. People with big hands, or people with small hands who don't mind using two hands on their phones.
LG Optimus G Pro Review: The Fastest Big Phone Out There

Design

It is, frankly, so much like Samsung's Note II that the two could play a Freaky Friday-style prank on their owners.. It's got Samsung's classic rounded, glossy, plastic back. Up front there's a home button that you physically press down, which is flanked by a menu button and a back button. There is a very thin bezel up front, which is a nice look. The biggest difference between it and the Note II is the lack of a built-in stylus. (Above, from left to right: Galaxy Note II, Optimus G Pro, and the Galaxy S4.)

Using It

While the phone is decidedly quick, there's just no getting around how unwieldy it is. One-handing it is a difficult proposition. I have larger-than-average hands, and it's a real strain to get into a position where my thumb can reach both the top and bottom of the screen. It was possible for me, but just barely. It also feels extremely prominent in your pants pocket. Every time I bent down to tie my shoes I was wondering if the screen or my pocket would break.

To be fair to the the Optimus G Pro, these issues aren't unique to this phone. It's a big-phone problem, and one that hasn't stopped people from buying the Galaxy Note or Note II.

LG Optimus G Pro Review: The Fastest Big Phone Out There

The Best Part

It is very, very fast. Right up there with the HTC One and the Samsung Galaxy S4. It flies though home screens, app drawers, and opening applications. HD games (such as Dead Trigger) play like butter. It actually feels a little faster than the S4, and just slightly slower than the One.

LG Optimus G Pro Review: The Fastest Big Phone Out There

Tragic Flaw

Good God, LG really needs to smarten up its software or (more preferably) just give up and let Android do its thing. LG's skin is exceptionally unintuitive and bad. Example: The app drawer is just a clutter mass of apps without any order by default. Luckily, you can choose to sort them alphabetically. Unluckily, any new apps you install still get stuck at the back, regardless of alphabetical order. This is dumb. The menu system's layout is perplexing, and the remote control app (it has an IR blaster) is about as good as the app on the HTC One or S4, which is to say, not good.

There's a whole quick menu in the notification panel (boosted from Samsung), quick apps which can hover over your other apps (boosted from Samsung), and even an option that can tell when you're looking at it so the screen stays on (again, boosted from Samsung). What it can't do is something simple like auto-adjust your screen's brightness to the ambient lighting. The option is there, it just doesn't work. At all. The Optimus G Pro's keyboard has the worst auto-correct on any mobile device I've ever used. The one positive is that LG's bad software somehow manages not to slow the phone down at all (can't say the same for Samsung's TouchWiz), but it's still awful. Replacing the homescreen with Nova Launcher and replacing the keyboard with SwiftKey 4 solves some, but not all, of these problems.

This Is Weird...

The phone has a physical button on the upper left side called the QuickButton. By default it's set to take a screen cap of whatever is on screen so you can then draw notes on it with your finger. Pretty much useless. Luckily, you can remap it in the settings so it opens up your camera application, and while it will work as a shutter button, technically, it doesn't have a two-stage press to it, so it doesn't work very well.

Test Notes

  • We tested the Optimus G Pro on AT&T's LTE network in NYC and the SF Bay Area, and in both locations it got better than average reception, and solid data speeds when it was on the LTE network. We got 25Mbps downloads and 15Mbps uploads when we had a strong signal.
  • The screen is very nice. Text looks great on it, as do videos. It's not as good as the screen on the One or the S4, but it's certainly better than the screen on the Note II, which isn't a surprise given that it's 1080p vs 720p, both at 5.5 inches.
  • Despite the king-sized 3140mAh battery, the phone's battery life is fairly middle-of-the-road. That screen sucks up a lot of juice. On days of heavier use, I'd only make it to about 6pm. When I used it less, it'd go well past midnight. Your mileage may vary.
  • Despite the 13MP camera in tow, photos are just okay. Shots are reasonably sharp, but colors tend to be washed out, and it really struggles with contrast. It does a better job in low light than the Galaxy S4, but it doesn't come anywhere near the HTC One or Nokia Lumia 900. (Some samples.)

LG Optimus G Pro Review: The Fastest Big Phone Out There

Should I Buy It?

If you're absolutely sold on owning a phone this big, well, it's the best giant phone presently out there. That said, Samsung is bound to release a Galaxy Note III in the months to come, and HTC is rumored to be unveiling a big one, too, so if you can wait, do. Or just get an HTC One or a Galaxy S4. Their screens aren't that much smaller and both phones are infinitely more useable because of simple ergonomics. We'd definitely recommend either of those phones (and the Nexus 4, and the iPhone 5) over the Optimus G Pro. That said, if you want something with size and speed and you want it right now, have at it. [LG]

  • LG Optimus G Pro Specs

    ? Network: AT&T
    ? OS: Android 4.1 with LG's skin
    ? CPU: 1.7 GHz quad-core Snapdragon 600
    ? Screen: 5.5-inch 1920x1080 IPS LCD (401PPI)
    ? RAM: 2GB
    ? Storage: 32GB + micro SD up to 64GB
    ? Camera: 13MP rear / 2MP front
    ? Battery: 3149 mAh
    ? Dimensions: 5.91 x 3.00 x 0.37 inches
    ? Weight: 5.64 ounces
    ? Price: Starts at $200 with a two-year contract

Source: http://gizmodo.com/lg-optimus-g-pro-review-the-fastest-big-phone-out-ther-510096255

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Official: New bank agency needs treaty change

FRANKFURT, Germany (AP) ? A top official with Germany's central bank says the EU will have to change its basic treaties if a proposed a new agency to wind down busted banks is to "stand on firm ground."

Bundesbank vice-president Sabine Lautenschlaeger said in a speech Tuesday that while European Union definitely needs the agency, but "a change in the basic law is needed."

A treaty change could take years and delay a key part of European banking reform aimed at preventing future crises. European officials say the new agency would keep banking failures and subsequent bailouts from dumping added debt on national governments ? a key problem in the eurozone's financial and economic crisis.

Lautenschlaeger's statements backed the position taken by German Finance Minister Wolfgang Schaeuble.

Source: http://news.yahoo.com/official-bank-agency-needs-treaty-change-090943053.html

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